Lenovo ThinkCentre M75s Gen 2

  • Up to AMD Ryzen™ 9 PRO 3900
  • Up to Windows® 11 Pro
  • Up to AMD Radeon™ RX 550X
  • Up to 128GB DDR4-3200, four DIMMs
  • Up to three drives, 1x 2.5″/3.5″ HDD + 1x 2.5″ HDD + 1x M.2 SSD

Ports & Slots

  1. Power button
  2. Optional 3-in-1 card reader
  3. Mic
  4. Headphone / mic combo
  5. USB-C 3.2 Gen 1
  6. 2 x USB 3.2 Gen 1
  7. 2 x USB 3.2 Gen 2
  8. Audio-out
  9. 2 x DisplayPort
  10. HDMI
  11. Serial
  12. RJ45
  13. 4 x USB 2.0
  14. Power-in


Shown with T34w monitor, wireless keyboard and mouse sold separately

Power to work

The ThinkCentre M75s Gen 2 desktop will breeze through your toughest tasks with up to an AMD Ryzen™ 7 PRO processor and up to 128GB DDR4 memory. Multitask, create content, and crunch data easily, improving productivity and the bottom line.

Steadfast security

The Thinkcentre M75s Gen 2 small form factor desktop’s discrete Trusted Platform Module (dTPM) chip encrypts critical information and enables hardware authentication. BIOS-based Smart USB Protection prevents unauthorized access via peripheral. And AMD GuardMI technology enables power-on-to-power-off data protection with a co-processor inside the AMD Ryzen™ PRO CPU.

Convenience guaranteed

The ThinkCentre M75s Gen 2 SFF offers plenty of convenient features to help users be more comfortable and productive. A rapid-charging USB port enables fast data transmission and device charging, even when the PC is in sleep mode. Turn on the desktop with a simple key stroke. Connect multiple peripherals to a variety of ports, for seamless multitasking. Easily manage updates, diagnostics, and security from a remote location.

Energy-efficient and reliable

The M75s Gen 2 has a minimal footprint on the environment as well as on your desk. It meets global sustainability standards for Energy Star® 8.0, EPEAT® Silver, and TCO 8.0. And it’s designed and rigorously tested for durability and reliability.

Order yours today

Contact Us or call us directly at 800-667-6590 for a custom Lenovo ThinkCentre M75s Gen 2 configuration today!

Processor / Processor Family

AMD Athlon™ or AMD Ryzen™ 3 / 5 / 7 Processor

Processor / Processor

AMD Athlon Gold PRO 3150G (4C, 4T, 3.5GHz, 3.9GHz, 2MB L2 / 4MB L3)
AMD Ryzen 3 5300G (4C, 8T, 4.0GHz, 4.2GHz, 2MB L2 / 8MB L3)
AMD Ryzen 3 PRO 4350G (4C, 8T, 3.8GHz, 4.0GHz, 2MB L2 / 4MB L3)
AMD Ryzen 3 PRO 5350G (4C, 8T, 4.0GHz, 4.2GHz, 2MB L2 / 8MB L3)
AMD Ryzen 5 PRO 4650G (6C, 12T, 3.7GHz, 4.2GHz, 3MB L2 / 8MB L3)
AMD Ryzen 5 PRO 5450G (6C, 12T, 3.9GHz, 4.4GHz, 3MB L2 / 16MB L3)
AMD Ryzen 7 PRO 4750G (8C, 16T, 3.6GHz, 4.4GHz, 4MB L2 / 8MB L3)
AMD Ryzen 7 PRO 5750G (8C, 16T, 3.8GHz, 4.6GHz, 4MB L2 / 16MB L3)

Operating System / Operating System

Windows 11 Home
Windows 11 Pro

Graphics / Graphics

Integrated AMD Radeon Graphics

Chipset / Chipset

AMD PRO 565 chipset

Memory / Max Memory

Up to 128GB DDR4-3200

Memory / Memory Slots

Four DDR4 DIMM slots, dual-channel capable

Memory / Memory Type


Storage / Storage Support

Up to three drives, 1x 2.5"/3.5" HDD + 1x 2.5" HDD + 1x M.2 SSD
– 2.5" HDD up to 1TB each
– 3.5" HDD up to 2TB
– M.2 SSD up to 2TB

Storage / Storage Type

2.5" SATA HDD (SATA 6Gb/s, 7.2K)
3.5" SATA HDD (SATA 6Gb/s, 7.2K)
M.2 2242 SSD (PCIe NVMe PCIe 3.0 x2)
M.2 2242 SSD (PCIe NVMe PCIe 3.0 x4)
M.2 2280 SSD (PCIe NVMe PCIe 3.0 x4, Opal)
M.2 2280 SSD (PCIe NVMe PCIe 4.0 x4 Value, Opal 2.0)
M.2 2280 SSD (PCIe NVMe PCIe x4, Opal 2.0)

Storage / RAID

RAID 0/1 support for HDDs

Removable Storage / Optical

DVD-ROM, SATA 1.5Gb/s, slim (9.0mm)
DVD burner (DVD±RW), SATA 1.5Gb/s, slim (9.0mm)

Removable Storage / Card Reader

3-in-1 card reader (SD, SDHC, SDXC)
No card reader

Multimedia / Audio Chip

High Definition (HD) Audio, Realtek® ALC623-CG codec

Multimedia / Speakers

No speakers
Single speaker, 1W x1

Power Supply / Power Supply


Input Device / Keyboard

Lenovo Traditional Keyboard (USB connector), black

Input Device / Mouse

Lenovo Calliope Mouse (USB connector), black

Mechanical / Form Factor

SFF (8.2L)

Mechanical / Dimensions

92.5 x 297.7 x 339.5 mm

Mechanical / Weight

5.3 kg

Mechanical / Case Colour


Mechanical / Bays

1x 2.5" disk bay (bay comes with disk)
1x 3.5" disk bay
1x slim ODD bay

Mechanical / Expansion Slots

One PCIe 3.0 x16, low-profile (length < 155mm, height < 68mm)
One PCIe 3.0 x1, low-profile (length < 155mm, height < 68mm)
Two M.2 slots (one for WLAN, one for SSD)
Two dummy slots, only brackets for optional port extension

Mechanical / EOU

EOU design for chassis open, M.2 SSD, HDD, ODD, memory, and PCIe extension card

Mechanical / Stand

Vertical stand
No stand

Mechanical / Others

(Optional) Dust filter
Supports Smart Power On

Network / Onboard Ethernet

Gigabit Ethernet, Realtek RTL8111EPV, 1x RJ-45, supports Wake-on-LAN
Gigabit Ethernet, Realtek RTL8111HN, 1x RJ-45, supports Wake-on-LAN

Network / Optional Ethernet

Gigabit Ethernet, Bitland BN8E88, 1x RJ-45, PCIe x1
Gigabit Ethernet, Bitland RTL8111FP, 1x RJ-45, PCIe x1
No optional Ethernet

Network / WLAN + Bluetooth

Realtek RTL8822CE, 802.11ac Dual Band 2×2 Wi-Fi® + Bluetooth® 5.0, M.2 card
Intel® Wireless-AC 9260, 802.11ac Dual Band 2×2 Wi-Fi + Bluetooth 5.0, M.2 card
Intel Wi-Fi 6 AX200, 802.11ax 2×2 Wi-Fi + Bluetooth 5.1, M.2 card[3]
MediaTek Wi-Fi 6 MT7921, 802.11ax 2×2 Wi-Fi + Bluetooth 5.1, M.2 Card[4]
Realtek Wi-Fi 6 RTL8852AE, 802.11ax Dual Band 2×2 Wi-Fi + Bluetooth 5.1, M.2 card[5]
No WLAN and Bluetooth

Ports / Front Ports

1x USB-C® 3.2 Gen 1
2x USB 3.2 Gen 1
2x USB 3.2 Gen 2
1x headphone / microphone combo jack (3.5mm)
1x microphone (3.5mm)

Ports / Optional Front Ports

1x card reader

Ports / Rear Ports

4x USB 2.0
1x HDMI 1.4b
2x DisplayPort 1.4
1x Ethernet (RJ-45)
1x line-out (3.5mm)
1x serial (9-pin)

Ports / Optional Rear Ports

2x USB-C 3.2 Gen 2 (support data transfer, via 2-port USB-C expansion card, PCIe x4)
2x USB 3.2 Gen 1 (via 2-port USB expansion card, PCIe x1)
2x USB 2.0 (via 2-port adapter)
1x parallel
1x serial
4x serial (via 4-port serial expansion card, PCIe x1)

Security / Security Chip

Discrete TPM 2.0, TCG certified

Security / Physical Locks

(Optional) E-lock
(Optional) Smart Cable Clip
Kensington® Security Slot™, 3 x 7 mm
Padlock Loop

Security / Chassis Intrusion Switch

Chassis intrusion switch
No chassis intrusion switch

Security / Fingerprint Reader

No fingerprint reader

Security / BIOS Security

Administrator password
Power-on password
Hard disk password
Boot sequence control
Boot without keyboard and mouse
Smart USB protection (allows keyboard / mouse only, blocks all storage devices)
Individual USB port disablement

System Management / System Management

DASH 1.2

Warranty / Base Warranty

1-year courier or carry-in service
1-year limited onsite service
3-year limited onsite service


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